According to the CDC more than 57% of Americans are overweight. That’s one in every six people. The World Health Organization reports more than 300 million people are obese worldwide.
The CDC also reports that every year more than 300,000 deaths occur prematurely from obesity costing billions of dollars for health related problems.
More than 50% of Americans diet every year, even more spend more than $300 million every year on weight loss products. Yet of these numbers only 5% succeed.
MSG Damaging the Hypothalamus, a Vital Regulator of Weight in the Brain
Before the 1970s researchers were linking obesity in lab animals to the damage of the hypothalamus by a flavor enhancer released in the US in the late 1940s.
The hypothalamus, a complex region of the brain, regulates the endocrine system, controls the appetite, thirst, body temperature, fatigue and body cycles and critical for memory and learning.
The appetite is regulated by a complex process that involves the hormones regulated by the hypothalamus, the gastrointestinal tract and the nervous system.
The hypothalamus picks up information from the gastrointestinal tract and uses several hormones such as leptin (inhibits appetite), cholecystokinin (suppresses hunger), orexin (increases the craving for food) and gherlin (promotes food intake) to either increase or decrease the appetite.
For example, when leptin is suppressed, uncontrolled food intake develops resulting in obesity. When cholecystokinin is overstimulated, anorexia ensues. Brain cells sensitive to orexin are overstimulated by glutamate, become damaged, malfunction and cause food cravings. Any stimulation of the lateral side of the hypothalamus will increase food intake.
The lack of a blood brain barrier around the hypothalamus makes it vulnerable to excito-toxins like MSG. The blood brain barrier, made up from densely packed cells, protects the brain from toxic substances and microorganisms circulating in the blood stream.
Because MSG is cumulative excessive concentrations of glutamate will overexcite the surrounding nerve cells and lead to cell damage and cell death.
Research Gives Evidence of Brain Damage As MSG Accumulates
In 1969 Dr. John Olney, a neuroscientist and psychiatrist, found that MSG not only caused brain lesions, it also damaged the hypothalamus and the dendrites in the brain causing obesity, endocrine abnormalities, stunted growth, infertility, seizures, behavioral and cognitive changes and memory loss.
He also found that the negative effects increased as MSG accumulated from chronic use causing an expansion of damage in the brain; and that the developing neonatal brain and the elderly brain were even more susceptible.
Other studies have shown that lab animals, exposed to monosodium glutamate while in the womb, developed abnormally and tended to be grossly obese, short, and had problems with sexual reproduction.
Studies show that continual exposure to excessive glutamate causes the degeneration of specific brain cells that lead to dementia. Consequently, maintaining low glutamate concentrations in the brain is crucial to the normal function of the brain and nervous system.
By 1980 the scientific community accepted as fact that MSG caused brain lesions and damage to the hypothalamus and dendrites. This prompted the glutamate industry to take a different approach by working with the FDA to maintain the GRAS (generally recognized as safe) level used for determining the toxicity of a chemical in spite of its damaging effects.
With the FDA supporting the glutamate industry, the addition of MSG into food and how it is disclosed on labels is poorly regulated so things like actual brain pills are very legal.